5 Popular Drugs That Cause Liver Damage (Avoid Overuse!)
Nonsteroidal anti-inflammatory drugs (NSAIDs): These include ibuprofen (Advil, Motrin), naproxen (Aleve), and aspirin. Regular use or exceeding recommended dosages can increase the risk of liver damage.
Prescription medications:
Antibiotics: Amoxicillin-clavulanate (Augmentin), erythromycin, and tetracyclines are some examples.
Anti-seizure medications: Phenytoin (Dilantin), carbamazepine (Tegretol), and valproic acid (Depakote) are among the potential culprits.
Anti-tuberculosis drugs: Isoniazid and rifampin carry a risk of liver injury, especially when combined with other medications.
Antidepressants: Certain antidepressants, such as amitriptyline (Elavil) and nortriptyline (Pamelor), can affect the liver.
Statins: These cholesterol-lowering medications can rarely cause liver problems, especially in high doses.
Hormonal medications: Birth control pills and anabolic steroids can impact liver function.
Antifungal medications: Ketoconazole and fluconazole are known to cause liver damage in some cases.
Other substances:
Dietary supplements: Workout supplements, fat burners, and green tea extracts are examples that might contain undisclosed ingredients or interact with other medications, leading to liver problems.
Alcohol: Excessive alcohol consumption is a major contributor to liver damage and disease.
Illegal drugs: Cocaine, PCP, and other illicit substances can significantly harm the liver.
It’s important to note that the risk of liver damage from any medication varies depending on individual factors, dosage, and underlying health conditions. Always follow your doctor’s instructions and inform them about all medications and supplements you are taking to minimize the potential for liver complications.
Here are some additional resources you might find helpful:
MedlinePlus: https://www.froedtert.com/stories/drug-induced-liver-injury-causes-treatment-options
Froedtert & MCW Health Network: https://www.froedtert.com/gastroenterology/liver-disease
GoodRx: https://www.goodrx.com/conditions/liver-disease