What is Nephrotic Syndrome? Top Symptoms, Treatment, and Causes You SHOULD Know!

  • Proteinuria: This is the hallmark symptom of nephrotic syndrome and can be detected through a urine test.
  • Edema: Fluid retention, particularly in the legs, ankles, feet, and around the eyes, is another common symptom.
  • Foamy urine: Due to the presence of protein, the urine may appear frothy or bubbly.
  • Fatigue: Low protein levels in the blood can lead to fatigue and weakness.
  • Loss of appetite: Protein loss can also cause a decreased appetite.
  • High cholesterol and triglycerides: The liver may produce more cholesterol and triglycerides to compensate for the lost protein, leading to high levels in the blood.
  • Increased susceptibility to infections: Low protein levels can weaken the immune system, making you more prone to infections.

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Nephrotic syndrome symptoms

Causes:

Several conditions can damage the glomeruli and cause nephrotic syndrome. Some of the most common causes include:

  • Minimal change disease: This is the most common cause of nephrotic syndrome in children. The cause is unknown, but it is thought to be an autoimmune reaction.
  • Focal segmental glomerulosclerosis (FSGS): This is a scarring of the glomeruli that can be caused by various factors, including infections, genetic conditions, and medications.
  • Membranous nephropathy: This is an autoimmune disease that attacks the glomerular basement membrane, a thin layer that helps filter blood.
  • Diabetes: Long-term, uncontrolled diabetes can damage the kidneys and lead to nephrotic syndrome.
  • Lupus: This autoimmune disease can affect various organs, including the kidneys, and cause nephrotic syndrome.
  • Amyloidosis: This is a condition where abnormal proteins build up in various organs, including the kidneys, and can damage the glomeruli.

Treatment:

Treatment for nephrotic syndrome depends on the underlying cause. In some cases, the underlying cause can be treated and the nephrotic syndrome will resolve on its own. However, in other cases, lifelong treatment may be necessary.

Some common treatment options include:

  • Corticosteroids: These medications can help reduce inflammation in the glomeruli and decrease proteinuria.
  • Immunosuppressant drugs: These medications can suppress the immune system and prevent it from attacking the glomeruli.
  • Diuretics: These medications can help remove excess fluid from the body and reduce edema.
  • Blood pressure medications: High blood pressure can worsen kidney damage, so it is important to control blood pressure with medication if necessary.
  • Diet changes: A low-salt diet can help reduce fluid retention.

Living with nephrotic syndrome:

Nephrotic syndrome can be a challenging condition to live with. However, with proper treatment and lifestyle changes, most people with nephrotic syndrome can lead healthy and productive lives.

It is important to work closely with your doctor to manage your condition and prevent complications. Regular follow-up appointments are essential to monitor your progress and adjust your treatment plan as needed.

Here are some additional tips for living with nephrotic syndrome:

  • Get plenty of rest.
  • Eat a healthy diet.
  • Avoid strenuous activity.
  • Maintain a healthy weight.
  • Don’t smoke.
  • Limit alcohol intake.
  • Manage stress.

I hope this information is helpful. Please let me know if you have any other questions.